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The science behind the formula

Every ingredient below is listed with its exact dose, at the level used in clinical research. No proprietary blends. If a brand will not tell you how much of something is in the tub, there is usually a reason.

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SYSTEM 01
Acetylcholine signaling
The chemistry of attention. It is what your brain draws on when you hold a thought in place long enough to finish it.*
SYSTEM 02
Balanced stress response
So deep work is not fighting your nervous system for the whole afternoon.*
SYSTEM 03
Calm alertness
The state between sedation and anxiety. It is where focus actually lives.*
THE ACTIVES · FIVE COMPOUNDS

The five that do the work

Each one is here for a reason, at a dose you can check against the research.
INGREDIENT NO. 01

CDP Choline

Cytidine diphosphate choline
550 MG
At the level used in clinical research. The single largest active dose in the formula.
CDP Choline

If Nootrify has an anchor ingredient, this is it. CDP Choline supports the production of acetylcholine, the neurotransmitter your brain draws on when you concentrate.*

How it works

CDP Choline is a direct precursor to acetylcholine. It also contributes to phosphatidylcholine, a structural component of the membranes your neurons are built from. So it supports both the signal and the hardware the signal runs through.*

What it supports
  • Supports acetylcholine production*
  • Plays a role in attention regulation*
  • Supports working memory and everyday recall*
  • Helps maintain healthy neural cell membranes*
RESEARCH
INGREDIENT NO. 02

Lion's Mane

Hericium erinaceus, organic fruiting body extract
400 MG
Fruiting body, not mycelium on grain. The distinction matters.
Lion's Mane

The long game ingredient. Lion's Mane contains hericenones and erinacines, compounds studied for their role in supporting the brain's own maintenance processes.*

How it works

These compounds are researched for their role in supporting nerve growth factor signaling, which is part of how the brain forms and maintains connections. This is a weeks to months process, not a same day effect, which is exactly why Nootrify is built around a 16 week horizon.*

What it supports
  • Supports the brain's natural maintenance processes*
  • Plays a role in healthy neural function*
  • Supports working memory over consistent use*
RESEARCH
INGREDIENT NO. 03

Ashwagandha

Withania somnifera, root
300 MG
Organic root powder.
Ashwagandha

The reason your afternoon does not feel like a fight. Ashwagandha is an adaptogen that helps maintain a balanced stress response.*

How it works

Ashwagandha contains withanolides, which are studied for their role in supporting the HPA axis, the system that governs your cortisol rhythm. Clinical trials measure this recalibration around week 8 to 12, which is why month two is when most people say the days stopped feeling steep.*

What it supports
  • Helps maintain a balanced stress response*
  • Promotes a sense of calm during demanding work*
  • Helps maintain healthy cortisol rhythm*
RESEARCH
INGREDIENT NO. 04

Rhodiola Rosea

Rhodiola rosea root, standardized to 3% salidroside
200 MG
Standardized extract. The percentage is on the label because it changes what you are actually getting.
Rhodiola Rosea

For the back half of the session. Rhodiola is an adaptogen studied for its role in helping maintain mental stamina during periods of occasional fatigue.*

How it works

Salidroside and rosavins are studied for their role in supporting cellular energy metabolism and helping the body adapt to occasional stress. Where Ashwagandha lowers the floor, Rhodiola holds the line later in the day.*

What it supports
  • Helps maintain mental stamina during occasional fatigue*
  • Helps the body adapt to occasional stress*
  • Supports sustained attention across a long session*
RESEARCH
INGREDIENT NO. 05

L-Theanine

Amino acid found naturally in green tea
100 MG
The only ingredient here that works on the very first serving.
L-Theanine

The one you feel first. L-Theanine promotes calm alertness, the state between sedation and anxiety where focus actually lives.*

How it works

L-Theanine is studied for its role in alpha wave activity and in modulating neurotransmitters including GABA and dopamine. It is also the reason Nootrify pairs cleanly with coffee: it supports a calm baseline underneath whatever caffeine you are already drinking.*

What it supports
  • Promotes calm alertness*
  • Supports attention under pressure*
  • Helps maintain composure during demanding work*
RESEARCH
THE SUPPORT PANEL

The rest of the panel

Vitamins and minerals the three systems run on.

The five actives above do the heavy lifting. These are the cofactors underneath them: the nutrients your body uses to build neurotransmitters and turn food into usable cellular energy. They are here in usable forms at meaningful amounts, not as label decoration.

100 MCG
Vitamin B12
as methylcobalamin
The active form. Supports cellular energy production and healthy nervous system function.*
1.3 MG
Vitamin B6
as pyridoxal-5-phosphate
A coenzyme in neurotransmitter synthesis, including dopamine and GABA.*
400 MCG DFE
Folate
as L-5-MTHF calcium
The methylated form. Supports the methylation cycle that neurotransmitter production depends on.*
1 MG
Thiamin
as thiamine HCL
Plays a role in turning carbohydrate into usable cellular energy.*
200 MG
Vitamin C
as ascorbic acid
Supports antioxidant status and helps maintain healthy immune function.*
25 MCG
Vitamin D
as cholecalciferol, from lichen
Vegan sourced. Helps maintain healthy mood balance and immune function.*
6.75 MG
Vitamin E
as DL-alpha tocopheryl acetate
A fat soluble antioxidant that helps protect cell membranes.*
30 MG
Sodium
naturally occurring
A small amount, which is part of why it mixes and drinks the way it does.
Why methylfolate, not folic acid

Nootrify uses L-5-MTHF, the methylated form of folate that the body can use directly. Synthetic folic acid has to be converted first, and a meaningful share of people convert it poorly. It costs more. We use it anyway, because the point of listing a dose is that the dose actually counts.*

Supplement facts panel Read the FAQ
*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. FOR ADULTS ONLY. CONSULT A PHYSICIAN IF PREGNANT OR NURSING, TAKING MEDICATION, OR MANAGING A MEDICAL CONDITION.

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Five actives at clinical doses, one daily mango drink. We support the system, so you can do the work.

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